Orally Dispersible Tablet Formulation Containing Vitamin D3 and Vitamin B12 for Enhanced Absorption and Compliance

Field of the Invention

The present invention relates to an orally dispersible tablet (ODT) formulation containing vitamin D3 (cholecalciferol) and vitamin B12 (methylcobalamin). This composition is designed to improve bioavailability, stability, and patient compliance, particularly for individuals with malabsorption issues or difficulty swallowing conventional tablets.

Background of the Invention

Vitamin D3 and vitamin B12 deficiencies are widespread and often require supplementation. Conventional tablets and capsules may have limitations in terms of absorption, especially for populations with gastrointestinal disorders or swallowing difficulties. Orally dispersible tablets (ODTs) offer a convenient alternative by allowing rapid dissolution in the mouth without the need for water, leading to faster absorption and improved patient adherence.

Summary of the Invention

The invention provides a novel orally dispersible tablet (ODT) formulation containing vitamin D3 and vitamin B12, utilizing excipients that enhance solubility, stability, and taste-masking properties. The composition ensures effective delivery of both vitamins through rapid oral mucosal absorption and gastrointestinal uptake.

Advantages of the Invention

• Rapid disintegration in the mouth without water.
• Improved bioavailability due to mucosal absorption.
• Enhanced stability of vitamin D3 and B12 in a dry matrix.
• Convenient dosage form for patients with dysphagia or poor gastrointestinal absorption.
• Increased patient compliance due to ease of use and pleasant taste.

This innovative orally dispersible tablet formulation offers a superior alternative to conventional vitamin D3 and B12 supplements by ensuring faster absorption, better stability, and higher patient adherence.