Antioxidant vitamins have the ability to neutralize free radicals capable of DNA damage, which makes cells become more vulnerable to HPV infection. The meta-analysis by Myung et al., which included 10,073 patients from 22 case-control studies, concluded that the intake of vitamin B12, vitamin E and beta-carotene was associated with a preventative effect on cervical cancer [105]. Similarly, the study by Guo et al. observed that elevated serum levels of vitamin E, vitamin C, and beta-carotene were associated with a reduced risk of cervical neoplasm [106]. In addition, the meta-analysis by Cao et al. has revealed that the association is dose-dependent; a 50 mg/day intake is correlated with a significantly lower risk [107].
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